Endocrine Abstracts

Introduction & Background: Pituitary adenomas represent 10-25% of all intracranial tumors. Their incidence is higher between the ages of 40-60 years and less frequent in young adults. The objective of this work was to evaluate the prevalence as well as the clinical and etiological profile of pituitary adenomas in young adults.Key words : pituitary adenoma- yount adult.Material and methods: Retrospective descriptive study of 21 ...

Introduction: Growth hormone deficiency (GHD) is a non-exceptional cause of short stature. Hormonal evaluation and hypothalamic-pituitary MRI are essential to establish the etiological diagnosis. The objective of our study is to assess the different pituitary lesions found in imaging in a group of children with GHD.Patients and methods: This is a retrospective longitudinal study of 22 cases of GHD who underwent pituitary MRI examination collected in the ...

Introduction: Polyuria-polydipsia syndrome is an uncommon problem in clinical practice defined by the combination of production of ‘abnormally’ large volumes of urine (>3 L/day in adults and 2 L/m2 in children) with the persistent intake of abnormally large quantities of fluids. The purpose of this study is to detail the clinical and etiological profile of polyuria-polydipsia syndrome in the Endocrinology-Diabetology Department of Oujda’s Universi...

Introduction: GH deficiency (GHD) is a rare etiology of short stature. The lack of early diagnosis and adequate treatment have adverse consequences, especially the small final height with the resulting psychological impact. The aim of this study is to identify some of the predictive factors influencing stature gain during the first year of GH therapy.Materials and methods: This is a retrospective longitudinal study of 14 cases of complete GHD collected i...

Introduction: Pituitary Stalk Interruption Syndrome (PSIS) is characterized by the presence of a thin or absent pituitary stalk, associated with hypoplastic or aplastic anterior pituitary and ectopic posterior pituitary (EPP) on magnetic resonance imaging (MRI). The objective of this study is to describe the clinical, hormonal and radiological aspects of PSIS.Patients and methods: This is a retrospective longitudinal study of 9 cases of PSIS collected in...

Introduction: Primary amenorrhea is an uncommon presentation in reproductive medicine requiring rigorous investigation. Primary amenorrhea is defined by the absence of menstrual cycle in girls after the age of 15 years, with or without the development of secondary sexual characteristics. The objective of the study is to determine the clinical, biological, etiological and therapeutic profile of primary amenorrhea in the Endocrinology-Diabetology department of Mohammed VI Univer...

Introduction: Cushing’s syndrome is a rare condition, resulting from chronic exposure to excessive circulating levels of glucocorticoids. This condition is highly associated with complications such as cardiovascular and metabolic disorders. This study aims to review the clinical characteristics, diagnosis and treatment of patients with ACTH-dependent Cushing’s syndrome.Material and Methods: A descriptive and comparative study carried out in t...

Introduction: Pituitary adenomas represent about 10 to 20% of all intracranial tumors. They are usually classified according to their size into pico-adenomas, micro-adenomas and macro-adenomas, but can also be classified according to their secretory properties into secreting or nonfunctional adenomas. In this study, we describe the clinica, paraclinica, therapeutic and evolution features of pituitary adenomas in our center.Material and methods: A retrosp...

Introduction: Metabolic abnormalities are common in pituitary adenomas and metabolic targeting is becoming a new therapeutic approach to the management of most tumor pathologies, especially pituitary tumors. The objective of this work was to assess the metabolic profile of non-functioning pituitary adenomas.Material and methods: A retrospective and descriptive study, over a period of 6 years, conducted in the Endocrinology-Diabetology and Nutrition depar...

Introduction: Growth Hormone deficiency (GHD) is a rare etiology of short stature. The lack of early diagnosis and adequate treatment have adverse consequences, especially the small final height with the resulting psychological impact. The aim of this study is to identify some of the predictive factors influencing stature gain during the first year of GH therapy.Matherials and methods: This is a retrospective and analytical study regarding 36 children wi...